Lithium Stimulation of Membrane-Bound Phospholipase C from PC 12 Cells Exposed to Nerve Growth Factor
โ Scribed by Cinzia Volonte; Efraim Racker
- Book ID
- 111174854
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 539 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-3042
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๐ SIMILAR VOLUMES
## Abstract Nerve growth factor (NGF) stimulates the uptake rate of the nonmetabolized amino acid ฮฑโaminoisobutyric acid (AIB) in the clonal PC12 pheochromocytoma cell line by 40โ70%. This effect reaches a maximum after a 1โhour incubation with the hormone and then drops over 50%, reaching a minimu
Both nerve growth factor (NGF) and K-252a stimulate the uptake of calcium into PC12 cells. Stimulation by either is prevented by pretreatment of the cells with the tumor promoter phorbol 12-myristate 13-acetate (PMA), suggesting an involvement of protein kinase C in the stimulation. The effect of PM
## Abstract Recent reports have highlighted that phosphoinositideโspecific phospholipase Cฮฒ1 expression is linked to neuronal differentiation in different experimental models. We sought to determine whether or not this is also true for nerve growth factor (NGF)โinduced neuronal differentiation of r