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Lithium perchlorate assisted one-pot three-component aminoalkylation of electron-rich aromatic compounds

✍ Scribed by Mohammad R Saidi; Najmoddin Azizi; M.Reza Naimi-Jamal


Book ID
104231780
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
237 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis


A one-pot, three-component, Mannich reaction of electron-rich aromatic compounds with in situ prepared iminium salts in 5 M ethereal lithium perchlorate gives good yields of aminoalkylated products at room temperature.


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ChemInform Abstract: Lithium Perchlorate
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Three Component Aminoalkylation of Aldehydes by Functionalized Organozinc Compounds Promoted by Lithium Perchlorate (LiClO4). -The one-pot synthesis of several N,N-dialkylamino esters like (IV) via a three component aminoalkylation procedure is reported. The reaction mechanism is discussed. -(SAIDI

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