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Lithium Binaphtholate-Catalyzed Enantioselective Enyne Addition to Ketones: Access to Enynylated Tertiary Alcohols

✍ Scribed by Cai, Hua; Nie, Jing; Zheng, Yan; Ma, Jun-An


Book ID
124055670
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
836 KB
Volume
79
Category
Article
ISSN
0022-3263

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Enantioselective Addition of Phenylacety
✍ Juan Ding; Zong-Xuan Shen; Xiao-Qing Luo; Wei-Yi Chen; Ya-Wen Zhang πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 69 KB πŸ‘ 2 views

## Abstract (__S__)‐(1‐Benzylpyrrolidin‐2‐yl)diphenylmethanol and cinchonine were evaluated as promotors in the asymmetric additions of phenylacetylene to ketones, in order to prepare chiral propargylic alcohols. Good yields (up to 89%) and moderate enantioselectivities (up to 77.9% __ee__) were ac