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Asymmetric Addition to Ketones: Enantioselective Formation of Tertiary Alcohols

✍ Scribed by Celina Garcia; Victor S. Martin


Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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Ru(CNtBu) , (CH,Ph),] (9) and [Ru(CNfBu),(SiMe,Cl),] (10) were both isolated in good yield (78 % and 71 %, respectively). NMR spectra indicate that 10, like 4 and 7, is formed as the trans isomer, while 9, surprisingly, is formed as the cis. Extensions of these reactions to more complex alkyls hav