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Lithiation of N -Boc-Protected Ferrocenylalkylamines: Preparation of Unsymmetrical 1,1‘-Disubstituted Ferrocenes

✍ Scribed by Chong, J. Michael; Hegedus, Louis S.


Book ID
126021912
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
88 KB
Volume
23
Category
Article
ISSN
0276-7333

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## Abstract magnified image Lithiation of __N__‐protected‐2,3‐dihydro‐1,4‐benzoxazines is described. Lithiation of __N__‐(__tert__‐butoxycarbonyl)‐2,3‐dihydro‐1,4‐benzoxazine (**1**) with BuLi/TMEDA occurred in the α‐position to nitrogen on the heterocyclic ring, leading to the unexpected ring‐ope