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Listeriolysin generates a route for the presentation of exogenous antigens by major histocompatibility complex class I

✍ Scribed by Ayub Darji; Trinad Chakraborty; Jürgen Wehland; Siegfried Weiss

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
585 KB
Volume
25
Category
Article
ISSN
0014-2980

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Targeting exogenous antigen into the MHC class I-restricted presentation pathway is a prerequisite for the induction of cytotoxic T lymphocytes (CTL) which have been shown to represent an important component of the protective and therapeutic immune response to viral infections and tumors. In this st