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Liquid chromatography–tandem mass spectrometry method for determination of aliskiren in saliva and its application to a clinical trial with healthy volunteers

✍ Scribed by Burckhardt, Bjoern B.; Tins, Jutta; Laeer, Stephanie

Book ID
121752641
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
854 KB
Volume
96
Category
Article
ISSN
0731-7085

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## Abstract A rapid and sensitive liquid chromatography–tandem mass spectrometry (LC/MS/MS) method to determine levonorgestrel in human plasma was developed and fully validated. After hexane–ethyl acetate (70:30, v/v) induced extraction from the plasma samples, levonorgestrel was subjected to LC/MS