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Liquid chromatography/tandem mass spectrometric method for the simultaneous determination of tobacco-specific nitrosamine NNK and its five metabolites

✍ Scribed by Hui-Ling Lee; Chiying Wang; Susana Lin; Dennis Paul Hsientang Hsieh

Book ID
116902405
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
149 KB
Volume
73
Category
Article
ISSN
0039-9140

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Liquid chromatographic/tandem mass spect
Liquid chromatographic/tandem mass spectrometric method for the determination of the tobacco-specific nitrosamine metabolite NNAL in smokers' urine
✍ Gary D. Byrd; Michael W. Ogden 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB 👁 1 views

## Abstract A specific and rapid liquid chromatographic/tandem mass spectrometric (LC/MS/MS) method was developed and validated for NNAL, a metabolite of the tobacco‐specific nitrosamine metabolite NNK. The metabolite was detected in smokers' urine with a limit of quantitation (LOQ) of 20 pg ml^−1^