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Liquid chromatography–tandem mass spectrometric assay with a novel method of quantitation for the simultaneous determination of bulaquine and its metabolite, primaquine, in monkey plasma

✍ Scribed by M Nitin; M Rajanikanth; J Lal; K.P Madhusudanan; R.C Gupta


Book ID
108497499
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
278 KB
Volume
793
Category
Article
ISSN
1873-376X

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## Abstract A simple and sensitive liquid chromatography‐tandem mass spectrometry (LC–MS/MS) method has been developed and validated for the quantitation of exemestane (Exe) and its main metabolite 17‐dihydroexemestane (DhExe) in human plasma. The analytes were extracted by protein precipitation wi