𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Liquid chromatography–electrospray tandem mass spectrometry investigations of fragmentation pathways of biliary 4,4′-methylenedianiline conjugates produced in rats

✍ Scribed by Kan Chen; Tammy R. Dugas; Richard B. Cole


Book ID
105891548
Publisher
Springer
Year
2008
Tongue
English
Weight
425 KB
Volume
391
Category
Article
ISSN
1618-2650

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Identification of metabolites of 4,4′-me
✍ Kan Chen; Tammy R. Dugas; Richard B. Cole 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 201 KB

## Abstract A capillary liquid chromatography‐electrospray tandem mass spectrometry (LC‐ES‐MS/MS) method was developed for the identification of metabolites of 4,4′‐methylenedianiline (diaminodiphenyl methane, (DAPM)) derived from exposure of vascular smooth muscle cells (VSMC) to this compound. Th

Detoxification of 4-hydroxynonenal (HNE)
✍ Giancarlo Aldini; Paola Granata; Marica Orioli; Enzo Santaniello; Marina Carini 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 234 KB

## Abstract Keratinocytes are potential targets of lipid peroxidation products (α,β‐unsaturated aldehydes) generated in the skin following UV exposure, among which the most abundant and toxic product is 4‐hydroxy‐__trans__‐2,3‐nonenal (HNE). The aim of this study was to investigate the ability of k

Detoxification of cytotoxic α,β-unsatura
✍ Giancarlo Aldini; Paola Granata; Marina Carini 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB

## Abstract Oxidation of polyunsaturated fatty acids containing phospholipids in tissue generates lipid hydroperoxides, which are further degraded to several products, among which unsaturated aldehydes such as 4‐hydroxy‐__trans__‐2‐nonenal (HNE) play an important role in mediating the pathological

Characterization of Conjugated Metabolit
✍ Kondo, Takahiro; Yoshida, Kiyoshi; Yoshimura, Yoshinobu; Motohashi, Michio; Tana 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 500 KB

Combined liquid chromatography and electrospray mass spectrometry (LC/ESI-MS) and tandem mass spectrometry (MS/MS) were used for the characterization of the conjugated metabolites (glucuronides) of a new angiotensin I1 receptor antagonist, candesartan cilexetil (TCV-116; ( f )-l-(cyclohexyloxycarbon