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Liquid Chromatography–Electrospray Ionization–Mass Spectrometric Method for the Determination of Hydrochlorothiazide in Human Plasma: Application to a Pharmacokinetic Study

✍ Scribed by Li, Lin; Sun, Jin; Yang, Ping; He, Zhonggui

Book ID
120015570
Publisher
Taylor and Francis Group
Year
2006
Tongue
English
Weight
145 KB
Volume
39
Category
Article
ISSN
0003-2719

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Highly sensitive method for the determin
Highly sensitive method for the determination of omeprazole in human plasma by liquid chromatography–electrospray ionization tandem mass spectrometry: application to a clinical pharmacokinetic study
✍ Shivva Vittal; Ramesh Ganneboina; Buddhadev Layek; Ravi Kumar Trivedi; Kishore K 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 705 KB

## Abstract A highly sensitive, rapid assay method has been developed and validated for the estimation of omeprazole (OPZ) in human plasma with liquid chromatography coupled to tandem mass spectrometry with electrospray ionization in the positive‐ion mode. The assay procedure involves alkalinizatio