Liposomal Methylprednisolone in Rats: Dose-Proportionality and Chronic-Dose Pharmacokinetics/Pharmacodynamics
โ Scribed by Elena V. Mishina; William J. Jusko
- Book ID
- 110344762
- Publisher
- Springer US
- Year
- 1996
- Tongue
- English
- Weight
- 903 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0724-8741
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
BMS-204352 is a novel maxi-K channel opener that is being developed for the treatment for stroke. The current study was designed to evaluate the dose proportionality and pharmacokinetics of BMS-204352 in rats. In an open, parallel fashion, sixteen rats per gender received a single intraarterial dose
A single-blind study was conducted in 10 healthy male subjects. Each subject was tested with four single oral doses of capsules containing 25, 50, 100, 200mg almitrine bismesylate and one dose of placebo. Blood samples were drawn as a function of time and the concentration of almitrine in plasma was