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Liposomal gene delivery: A complex package

✍ Scribed by Huang, Leaf; Li, Song


Book ID
109905743
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
338 KB
Volume
15
Category
Article
ISSN
1087-0156

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To increase cationic liposome-mediated intravenous DNA delivery extruded DOTAP:cholesterol liposomes were used to form complexes with DNA, resulting in enhanced expression of the chloramphenicol acetyltransferase gene in most tissues examined. The DNA:liposome ratio, and mild sonication, heating, an