Transmission models for high density lipoprotein (HDL) were evaluated in the Berkeley data set through segregation analyses using S.A.G.E. These preliminary analyses indicate that among the models fitted, an additive model with non-Mendelian transmission probabilities provides a good fit for HDL, su
Lipoprotein subclasses in genetic studies: The Berkeley data set
β Scribed by Dr. Ronald M. Krauss; Paul T. Williams; Patricia J. Blanche; Adelle Cavanaugh; Laura G. Holl; Melissa A. Austin
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 398 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0741-0395
No coin nor oath required. For personal study only.
β¦ Synopsis
In conjunction with a study examining the inheritance of LDL subclass patterns in a healthy population, measurements of lipids, lipoproteins, and lipoprotein subclasses were performed in 301 individuals in 27 kindreds. Questionnaires were used to obtain information on use of medications, hormones, cigarettes, and alcohol. Laboratory data from this study (the Berkeley data set) include measurements of LDL and HDL size subclasses by nondenaturing gradient gel electrophoresis, and measurement of apolipoprotein A-I by radial immunodiffusion.
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