๐”– Bobbio Scriptorium
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Segregation analysis for high density lipoprotein in the berkeley data

โœ Scribed by Dr. L. Adrienne Cupples; Richard H. Myers

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
354 KB
Volume
10
Category
Article
ISSN
0741-0395

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โœฆ Synopsis

Transmission models for high density lipoprotein (HDL) were evaluated in the Berkeley data set through segregation analyses using S.A.G.E. These preliminary analyses indicate that among the models fitted, an additive model with non-Mendelian transmission probabilities provides a good fit for HDL, suggesting the possibility of a significant environmental component in the transmission of HDL. After adjustment for triglyceride, however, Mendelian models for a major gene seem to provide as good a fit as non-Mendelian models but the results do not permit distinction between a dominant model and an additive model.

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