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Lipopolysaccharide induces substance P in sympathetic ganglia via ganglionic interleukin-1 production

✍ Scribed by Annette M. Shadiak; Christopher D. Carlson; Minzhen Ding; Ronald P. Hart; G. Miller Jonakait

Book ID
119108828
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
756 KB
Volume
49
Category
Article
ISSN
0165-5728

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## Abstract The present study establishes that tumor necrosis factor‐α (TNF‐α) induction of sympathetic substance P (SP) requires sequential induction of both interleukin (IL‐1) and leukemia inhibitory factor (LIF). TNF‐α dose‐dependently induces SP, an induction that is secondory to an increase in