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Lipopeptide induces apoptosis in fungal cells by a mitochondria-dependent pathway

✍ Scribed by Gaofu Qi; Fayin Zhu; Peng Du; Xiufen Yang; Dewen Qiu; Ziniu Yu; Jingyuan Chen; Xiuyun Zhao

Book ID
116832281
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
572 KB
Volume
31
Category
Article
ISSN
0196-9781

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## Abstract The mitochondria‐mediated apoptotic pathway is regulated by members of the Bcl‐2 family. Epidermal growth factor (EGF) induces Bad phosphorylation at Ser~112~ via mitogen‐activated protein kinase (MAPK), impairing its binding to Bcl‐2 and Bcl‐xL and interfering with their anti‐apoptotic