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Lipid Rafts and Oxidative Stress–Induced Cell Death

✍ Scribed by Morgan, Michael J.; Kim, You-Sun; Liu, Zhenggang

Book ID: 111691796
Publisher: Mary Ann Liebert
Year: 2007
Tongue: English
Weight: 319 KB
Volume: 9
Category: Article
ISSN: 1523-0864
DOI: 10.1089/ars.2007.1658

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## Abstract Oxidative stress is associated with β‐amyloid peptide (Aβ) accumulation in the brains of Alzheimer's disease patients. Aβ is generated upon the sequential proteolytic cleavage of transmembrane amyloid precursor protein (APP) by two membrane‐bound proteases, β‐secretase (BACE1) and the γ