Lipid peroxidation in early type 1 diabetes mellitus is unassociated with oxidative damage to DNA
β Scribed by Robert D. Hoeldtke; Kimberly D. Bryner; Linda L. Corum; Gerald R. Hobbs; Knox Van Dyke
- Book ID
- 119326067
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 110 KB
- Volume
- 58
- Category
- Article
- ISSN
- 1532-8600
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π SIMILAR VOLUMES
## Abstract Diabetic hyperglycemia is associated with increased production of reactive oxygen species (ROS). ROS reacts with DNA resulting in various products, such as 8βhydroxydeoxyguanosine (8βOHdG), that excrete in urine owing to DNA repair processes. Urinary 8βOHdG has been proposed as an indic
## Abstract ## Objective The aim of this study is to verify whether, early in the course of type 1 diabetes and assuming hyperglycemia as the only risk factor, women demonstrate a change in oxidative status due to an interaction between nitric oxide (NO) and uric acid production. ## Methods Thir