Lipid oxidation products in cell signaling
✍ Scribed by Gabriella Leonarduzzi; Melek C. Arkan; Hüveyda Başağa; Elena Chiarpotto; Alex Sevanian; Giuseppe Poli
- Book ID
- 114274375
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 245 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0891-5849
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The molecular mechanisms through which oxidized lipids and their electrophilic decomposition products mediate redox cell signalling is not well understood and may involve direct modification of signal-transduction proteins or the secondary production of reactive oxygen or nitrogen species in the cel
In the last decade, a multitude of secondary products have been identified from the radical and photosensitized oxidations of polyunsaturated lipids. These secondary products consist of oxygenated monomeric materials including epoxy-hydroperoxides, oxo-hydroperoxides, hydroperoxy epidioxides, dihydr