Lipid oxidation products and atherosclerosis
โ Scribed by Judith Berliner
- Book ID
- 114413457
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 135 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1537-1891
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๐ SIMILAR VOLUMES
4-Hydroxynonenal (HNE) is by far the most investigated aldehydic end-product of oxidative breakdown of membrane n-6 polyunsaturated fatty acids. Its potential involvement in the pathogenesis of atherosclerosis has been corroborated by its consistent detection in both oxidized LDL and fibrotic plaque
In the last decade, a multitude of secondary products have been identified from the radical and photosensitized oxidations of polyunsaturated lipids. These secondary products consist of oxygenated monomeric materials including epoxy-hydroperoxides, oxo-hydroperoxides, hydroperoxy epidioxides, dihydr