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Lipid-lowering and antioxidative activities of 3,4-di(OH)-cinnamate and 3,4-di(OH)-hydrocinnamate in cholesterol-fed rats

✍ Scribed by Jeong-Sun Lee; Myung-Sook Choi; Seon-Min Jeon; Tae-Sook Jeong; Yong Bok Park; Mi-Kyung Lee; Song-Hae Bok


Book ID
117074471
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
88 KB
Volume
314
Category
Article
ISSN
0009-8981

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## Abstract A preliminary study revealed that 3,4‐di(OH)‐hydrocinnamate (HC), a polyphenolic compound, lowered the plasma lipids in high‐cholesterol fed rats. Accordingly, this study was designed to test the lipid‐lowering efficacy of a synthetic derivative, 3,4‐di(OH)‐phenylpropionic (L‐leucine) a

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## Abstract The effect of 3,4‐di(OH)‐phenylpropionic acid (L‐phenylalanine methyl ester) amide (SL‐1063), a synthetic derivative of 3,4‐di(OH)‐cinnamate, on the cholesterol metabolism and antioxidant enzyme system was examined in rats. Diets that included either SL‐1063 (0.046%, w/w) or lovastatin