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Anticholesterolemic effect of 3,4-di(OH)-phenylpropionic amides in high-cholesterol fed rats

✍ Scribed by Soon-Ja Kim; Song-Hae Bok; Sangku Lee; Hye-Jin Kim; Mi-Kyung Lee; Yong Bok Park; Myung-Sook Choi


Book ID
113923580
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
223 KB
Volume
208
Category
Article
ISSN
0041-008X

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## Abstract A preliminary study revealed that 3,4‐di(OH)‐hydrocinnamate (HC), a polyphenolic compound, lowered the plasma lipids in high‐cholesterol fed rats. Accordingly, this study was designed to test the lipid‐lowering efficacy of a synthetic derivative, 3,4‐di(OH)‐phenylpropionic (L‐leucine) a

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## Abstract The effect of 3,4‐di(OH)‐phenylpropionic acid (L‐phenylalanine methyl ester) amide (SL‐1063), a synthetic derivative of 3,4‐di(OH)‐cinnamate, on the cholesterol metabolism and antioxidant enzyme system was examined in rats. Diets that included either SL‐1063 (0.046%, w/w) or lovastatin