Doxorubicin-loaded solid lipid nanoparti
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Keon Wook Kang; Myung-Kwan Chun; Ok Kim; Robhash Kusam Subedi; Sang-Gun Ahn; Jun
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Article
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2010
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Elsevier Science
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English
⚖ 374 KB
In the present study we developed doxorubicin-loaded solid lipid nanoparticles (SLN-Dox) using biocompatible compounds, assessed the in vitro hemolytic effect, and examined their in vivo effects on drug retention and apoptosis intensity in P-glycoprotein-overexpressing MCF-7/ADR cells, a representat