Lipase-Mediated Diastereoselective and Enantioselective Acetylations of 3-Substituted Cyclohexanols. -Lipase-mediated acetylation of a diastereomeric mixture of 3-substituted cyclohexanols (II)/(III) results in efficient resolution providing the acetates (V) in high enantiomeric excess. -
✦ LIBER ✦
Lipase-mediated esterification of racemic alcohols: A comparison of 2-substituted cyclohexanols and cyclopentanols
✍ Scribed by Marie Zarevúcka; Martin Rejzek; Zdeněk Wimmer; Jan Zima; Qiu-yu Zhao; Marie-Dominique Legoy
- Book ID
- 104656603
- Publisher
- Springer Netherlands
- Year
- 1995
- Tongue
- English
- Weight
- 240 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0141-5492
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✦ Synopsis
Esterification of five-and six-membered-ring-containing alcohols catalysed by three different lipases (those from porcine pancreas, Candida cylindracea and Geotrichum candidum) was studied. Some conversions gave high stereochemical purity, but all gave low yields.
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