## Abstract **BACKGROUND:** Reactions performed under solventโfree conditions give processes that are environmentally friendly, since most solvents are polluting agents. In this work, the performance of __Candida rugosa__ lipae (CRL) immobilized on styreneโdivinylbenzene (STYโDVB) or controlled po
Lipase-catalyzed synthesis of lysophosphatidic acid in a solvent free system
โ Scribed by Jeong Jun Han; Joon Stock Rhee
- Publisher
- Springer Netherlands
- Year
- 1995
- Tongue
- English
- Weight
- 421 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0141-5492
No coin nor oath required. For personal study only.
โฆ Synopsis
The direct, lipase-catalyzed esterifications of glycerol-3-phosphate in an organic solvent system and in a solvent free system were carried out. In a solvent free system only, LPA synthesis could be achieved within the acceptable reaction time. Open reaction system was preferable to closed reaction system for LPA synthesis. Yield of LPA isolated by silica gel column chromatography was 32.3%.
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Citronellol esterification catalyzed by Candida antarctica lipase is performed with high yields (74%) in a solvent-free medium. The use of dessicants gives a 10% yield enhancement and substrate excess consumption by adding calculated amounts of acetic acid lead to a 80% pure citronellyl acetate. Qua