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Lipase-catalyzed synthesis of lysophosphatidic acid in a solvent free system

โœ Scribed by Jeong Jun Han; Joon Stock Rhee


Publisher
Springer Netherlands
Year
1995
Tongue
English
Weight
421 KB
Volume
17
Category
Article
ISSN
0141-5492

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โœฆ Synopsis


The direct, lipase-catalyzed esterifications of glycerol-3-phosphate in an organic solvent system and in a solvent free system were carried out. In a solvent free system only, LPA synthesis could be achieved within the acceptable reaction time. Open reaction system was preferable to closed reaction system for LPA synthesis. Yield of LPA isolated by silica gel column chromatography was 32.3%.


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