Lipase-Catalyzed Enantioselective Acylation in a Halogen Free Ionic Liquid Solvent System.
β Scribed by Toshiyuki Itoh; Nozomi Ouchi; Shuichi Hayase; Yoshihito Nishimura
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 91 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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Enzymatic ester hydrolysis and ammoniolysis were performed as competitive reactions in methyl isobutyl ketone without a separate aqueous phase. The reaction system contained solid ammonium bicarbonate, which dissolved as water, ammonia, and carbon dioxide. During the reaction an organic liquid phase
## Abstract **BACKGROUND:** In this work we describe the synthesis of ethyl esters, commonly known as biodiesel, using refined soybean oil and ethanol in a solventβfree system catalyzed by lipase from __Thermomyces lanuginosus__. Central composite design and response surface methodology (RSM) were