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Lipase-Catalyzed Kinetic Resolution of α-Hydroxy-H-phosphinates.

✍ Scribed by Takehiro Yamagishi; Tetsuya Miyamae; Tsutomu Yokomatsu; Shiroshi Shibuya


Publisher
John Wiley and Sons
Year
2004
Weight
17 KB
Volume
35
Category
Article
ISSN
0931-7597

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Synthesis of Optically Active α-Hydroxy
✍ Waldemar Adam; Michael Lazarus; Alexandra Schmerder; Hans-Ulrich Humpf; Chantu R 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 322 KB 👁 1 views

The lipase-catalyzed acetylation of a broad spectrum of configurations of the 2-hydroxy acids 1 were assigned by comparison of the gas-chromatographic data with that of racemic 2-hydroxy acids 1 to their 2-acetoxy acids 2 was shown to proceed with high enantioselectivity. Thus, the literature-known