Pseudomonas fluorescens lipase (PFL) was used as catalyst for enzymatic resolution of 1-ethoxycarbonyl-2-hydroxy-cyclohexane. The resulting ester was used for the total synthesis of the novel enantiomerically pure 10-ethyl trinem.
✦ LIBER ✦
Lipase-catalyzed kinetic resolution of cis-1-diethylphosphonomethyl-2-hydroxymethylcyclohexane. Application to enantioselective synthesis of 1-diethylphosphonomethyl-2-(5′-hydantoinyl)cyclohexane
✍ Scribed by Tsutomu Yokomatsu; Nobuko Nakabayashi; Keita Matsumoto; Shiroshi Shibuya
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 474 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0957-4166
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