Lipase-catalyzed desymmetrization of meso-1,2-diaryl-1,2-diaminoethanes
✍ Scribed by Méndez-Sánchez, Daniel; Ríos-Lombardía, Nicolás; García-Granda, Santiago; Montejo-Bernardo, José; Fernández-González, Alfonso; Gotor, Vicente; Gotor-Fernández, Vicente
- Book ID
- 121756148
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 652 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0957-4166
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Asymmetric methanolysis of meso cyclic carboxylic anhydrides including hexahydrophthalic anhydride proceeded in toluene in the presence of (6R,7aS)-(2-aryl-6-hydroxy)hexahydro-1H-pyrrolo[1,2-c]imidazol-1-one to give the corresponding desymmetrized mono ester acids (e.g. (1S,2R)-2-(methoxycarbonyl)cy