The arymmeti syntheses of both enantiomers of 4and O-benql derivatives are reported z4 DIBAL and ZnCl2/DI aTmy-2qciohewnone and their 0-acetyl L stemaelective reducrionr of the ketosulfaides resulting in the sul'nylation of Al-cyciohexanedione ethylene monoketai, are the key steps in these syntheses
Lipase-catalyzed asymmetric synthesis of (R)- and (S)-4-tert-butyldimethylsilyloxy-2,6,6-trimethyl-2-cyclohexenone and their dihydro derivatives
โ Scribed by Akira Tanaka; Hiroshi Yamamoto; Takayuki Oritani
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 351 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0957-4166
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## Abstract Highโfield NMR studies of (1__S__, 4__R__, 6__R__)โ and (1__S__, 4__R__, 6__S__)โ1,3,3โtrimethylโ2โoxoโ6โ(2โoxopropyl)bicyclo[2.2.2]octane were carried out by oneโ and twoโdimensional methods. The stereochemical aspects of these molecules were studied through the application of the nucl