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Linking tyrosine kinases to Ras


Book ID
113407047
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
137 KB
Volume
3
Category
Article
ISSN
0962-8924

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The vav proto-oncogene encodes a 95 kDa protein which is expressed exclusively in hematopoietic cells. Analysis of the deduced amino acid sequence has revealed the presence of a src-homology 2 (SH2) domain, 2 SH3 domains, a cysteine-rich region with similarity to protein kinase C, and a region highl