Linkage Thermodynamics of Macromolecular Interactions
β Scribed by Frederic M. Richards, David S. Eisenberg and Peter S. Kim (Eds.)
- Publisher
- Academic Press
- Year
- 1998
- Tongue
- English
- Leaves
- 485
- Series
- Advances in Protein Chemistry 51
- Edition
- 1st
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.
β¦ Table of Contents
Content:
Edited by
Page iii
Copyright page
Page iv
Introduction
Pages ix-x
Enrico Di Cera, John T. Edsall
Electrostatic Contributions to Molecular Free Energies in Solution Original Research Article
Pages 1-57
Michael Schaefer, Herman W.T. Van Vlijmen, Martin Karplus
Site-Specific Analysis of Mutational Effects in Proteins Original Research Article
Pages 59-119
Enrico Di Cera
Allosteric Transitions of the Acetylcholine Receptor Original Research Article
Pages 121-184
Stuart J. Edelstein, Jean-Pierre Changeux
Deciphering the Molecular Code of Hemoglobin Allostery Original Research Article
Pages 185-253
Gary K. Ackers
Statistical Thermodynamic Linkage Between Conformational and Binding Equilibria Original Research Article
Pages 255-279
Ernesto Freire
Analysis of Effects of Salts and Uncharged Solutes on Protein and Nucleic Acid Equilibria and Processes: A Practical Guide to Recognizing and Interpreting Polyelectrolyte Effects, Hofmeister Effects, and Osmotic Effects of Salts Original Research Article
Pages 281-353
M. Thomas Record Jr., Wentao Zhang, Charles F. Anderson
Control of Protein Stability and Reactions by Weakly Interacting Cosolvents: The Simplicity of the Complicated Original Research Article
Pages 355-432
Serge N. Timasheff
Author Index
Pages 433-451
Subject Index
Pages 453-473
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