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Macromolecular Crystallography Protocols: Volume 1, Preparation and Crystallization of Macromolecules

✍ Scribed by Joseph E. Tropea, Scott Cherry (auth.), John M. Walker, Sylvie Doublié (eds.)


Publisher
Humana Press
Year
2007
Tongue
English
Leaves
282
Series
Methods in Molecular Biology 363
Edition
1
Category
Library

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✦ Synopsis


Macromolecular Crystallography Protocols, now in two volumes, examines major developments that have occurred since publication of the acclaimed first edition nearly a decade ago. Volume 1, Preparation and Crystallization of Macromolecules and Volume 2, Structure Determination, explore recent advances that have accelerated the pace of structural determination and made crystallography accessible to a broader range of investigators.

Volume 1 is composed of detailed protocols for the preparation and optimization of crystals, including tips from the experts on the best methods for inducing proteins to adopt their crystalline form. Volume 2 complements the first volume by addressing laboratory techniques for crystal handling and structural characterization, as well as computational techniques for data collection, phasing, and refinement. The volume concludes with a detailed and insightful survey of available crystallographic software. These volumes will be an indispensable reference for obtaining macromolecular crystals and determining their three-dimensional structure.

✦ Table of Contents


Front Matter....Pages i-xiii
Back Matter....Pages 1-19
....Pages 21-37

✦ Subjects


Cell Biology


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