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Linkage of epidermolytic hyperkeratosis to the type II keratin gene cluster on chromosome 12q

✍ Scribed by Compton, John G.; DiGiovanna, John J.; Santucci, Sandra K.; Kearns, Kathleen S.; Amos, Christopher I.; Abangan, Donita L.; Korge, Bernhard P.; McBride, O. Wesley; Steinert, Peter M.; Bale, Sherri J.


Book ID
109916419
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
557 KB
Volume
1
Category
Article
ISSN
1061-4036

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Mapping of a gene for epidermolytic palm
✍ AndrΓ© Reis; Wolfgang KΓΌster; Ralf Eckardt; Karl Sperling πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 611 KB

Epidermolytic palmoplantar keratoderma (EPPK) (VΓΆrner-Unna-Thost) is an autosomal dominantly inherited skin disease of unknown etiology characterized by diffuse severe hyperkeratosis of the palms and soles and, histologically, by cellular degeneration. We have mapped a gene for EPPK to chromosome 17