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Fine genetic mapping of diffuse non-epidermolytic palmoplantar keratoderma to chromosome 12q11-q13: exclusion of the mapped type II keratins

✍ Scribed by D. P. Kelsell; H. P. Stevens; P. E. Purkis; U. Talas; M. H. A. Rustin; I. M. Leigh


Book ID
111243937
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
80 KB
Volume
8
Category
Article
ISSN
0906-6705

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Mapping of a gene for epidermolytic palm
✍ AndrΓ© Reis; Wolfgang KΓΌster; Ralf Eckardt; Karl Sperling πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 611 KB

Epidermolytic palmoplantar keratoderma (EPPK) (VΓΆrner-Unna-Thost) is an autosomal dominantly inherited skin disease of unknown etiology characterized by diffuse severe hyperkeratosis of the palms and soles and, histologically, by cellular degeneration. We have mapped a gene for EPPK to chromosome 17