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Linkage data on affective disorders in an epidemiologic context

✍ Scribed by Dr. Elliot S. Gershon; Lynn R. Goldin

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 706 KB
Volume: 6
Category: Article
ISSN: 0741-0395
DOI: 10.1002/gepi.1370060136

No coin nor oath required. For personal study only.

✦ Synopsis

Recent data on chromosomal linkage markers in affective disorders indicate that single locus inheritance is involved in these disorders. The presence of a single locus has not been detectable using segregation analysis on family study data from large populations, possibly because of both heterogeneity and birth cohort and sex differences in diagnostic frequencies.

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