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Linkage betweenTcrb-Vand a gene responsible for deletion of Tcrb-V11 + T cells

โœ Scribed by Kyuhei Tomonari


Publisher
Springer-Verlag
Year
1990
Tongue
English
Weight
180 KB
Volume
32
Category
Article
ISSN
0093-7711

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Co-segregation of a gene encoding a dele
โœ Sue Fairchild; Andrew M. Knight; P. Julian Dyson; Kyuhei Tomonari ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 361 KB

A gene encoding the endogenous superantigen Mlsc, which deletes Tcrb-V3+ T cells in the NOD inbred mouse strain, was found to co-segregate with Mtv-3 on chromosome 11. This identifies a fourth gene encoding a deletion ligand for Tcrb-V3+ T cells and extends recently published observations in support