๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Linkage analysis of bronchial hyperreactivity and atopy with chromosome 11q13

โœ Scribed by Dr. Zilla Y. H. Wong; Dina Tsonis; Lynne van Herwerden; Joan Raven; Andrew Forbes; Michael J. Abramson; E. Haydn Walters; Stephen B. Harrap

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
438 KB
Volume
18
Category
Article
ISSN
0173-0835

No coin nor oath required. For personal study only.

โœฆ Synopsis

Linkage analysis of bronchial hyperreactivity and atopy with chromosome 1 lq13

There are two key clinical features of asthma: allergy and bronchial hyperreactivity (BHR). Some pedigree studies of atopy have indicated linkage with the high affinity IgE receptor (FceRI-P) gene on chromosome llq13, but others failed to confirm this linkage. We examined the genetic linkage of three polymorphic microsatellite markers to atopy and BHR in 120 affected sibling pairs recruited from the general community. We found no linkage to atopy at any of' the three llq13 loci studied. Our findings also do not favour linkage between BHR and loci approximately 8-9 cM either side of the FceRI-fi gene.

๐Ÿ“œ SIMILAR VOLUMES

Absence of linkage and linkage disequili
Absence of linkage and linkage disequilibrium to chromosome 15q11-q13 markers in 139 multiplex families with autism
โœ Salmon, Boyd; Hallmayer, Joachim; Rogers, Tamara; Kalaydjieva, Luba; Petersen, P ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 23 KB ๐Ÿ‘ 2 views

Chromosomal region 15q11-q13 has been implicated to harbor a susceptibility gene or genes underlying autism. Evidence has been derived from the existence of cytogenetic anomalies in this region associated with autism, and the report of linkage in a modest collection of multiplex families. Most recen

Exclusion of autosomal dominant dystonia
Exclusion of autosomal dominant dystonia gene from large regions of chromosomes 11p, 13q, and 21q by multi-point linkage analysis
โœ Dr. P. L. Kramer; L. Ozelius; J. F. Gusella; S. Fahn; K. K. Kidd; X. O. Breakefi ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 599 KB

Multi-point linkage analyses of autosomal dominant form of torsion dystonia with linkage groups on chromosomes llp, 13q, 21q are reported. Analyses are based on family data from a single, large, non-Jewish pedigree. Large portions of chromosomes l l p and 13q, and virtually the entire long arm of ch

Asplenia syndrome in a child with a bala
Asplenia syndrome in a child with a balanced reciprocal translocation of chromosomes 11 and 20 [46,XX,t(11;20)(q13.1;q13.13)]
โœ Freeman, Sallie B.; Muralidharan, Kasinathan; Pettay, Dorothy; Blackston, R. Dwa ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 25 KB ๐Ÿ‘ 3 views

We present a 6-year-old girl with a balanced 11;20 translocation [46,XX,t(11;20)(q13.1; q13.13)patl, asplenia, pulmonic stenosis, Hirschsprung disease, minor anomalies, and mental retardation. This case represents the second report of an individual with situs abnormalities and a balanced chromosome