✦ LIBER ✦
Exclusion of autosomal dominant dystonia gene from large regions of chromosomes 11p, 13q, and 21q by multi-point linkage analysis
✍ Scribed by Dr. P. L. Kramer; L. Ozelius; J. F. Gusella; S. Fahn; K. K. Kidd; X. O. Breakefield; I. B. Boerecki
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 599 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0741-0395
No coin nor oath required. For personal study only.
✦ Synopsis
Multi-point linkage analyses of autosomal dominant form of torsion dystonia with linkage groups on chromosomes llp, 13q, 21q are reported. Analyses are based on family data from a single, large, non-Jewish pedigree. Large portions of chromosomes l l p and 13q, and virtually the entire long arm of chromosome 21 are excluded from linkage with dystonia. Practical aspects of designing multipoint analyses are discussed.