LINGO-1 negatively regulates myelination by oligodendrocytes
โ Scribed by Mi, Sha; Miller, Robert H; Lee, Xinhua; Scott, Martin L; Shulag-Morskaya, Svetlane; Shao, Zhaohui; Chang, Jufang; Thill, Greg; Levesque, Melissa; Zhang, Mingdi
- Book ID
- 109940613
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 520 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1097-6256
- DOI
- 10.1038/nn1460
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๐ SIMILAR VOLUMES
Myelin basic protein (MBP) is one of the most important myelin components. Based on our previous shidies, we hypothesized that neurons might have regulatory effects on the production of MBP by oligodendrocytes, and we conducted studies designed to verify this hypothesis. Oligodendroglia-rich culture
## Abstract The analysis of the molecular mechanisms involved in the initial interaction between neurons and Schwann cells is a key issue in understanding the myelination process. We recently identified __Cthrc1__ (Collagen triple helix repeat containing 1) as a gene upregulated in Schwann cells up