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Linear regression model of DNA sequences and its application

✍ Scribed by Qi Dai; Xiao-Qing Liu; Tian-Ming Wang; Damir Vukicevic

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
412 KB
Volume
28
Category
Article
ISSN
0192-8651

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✦ Synopsis

Abstract

We constructed six new models to analyze the DNA sequences. First, we regarded a DNA primary sequence as a random process in t and gave three ways to define nucleotides' random distribution functions. We extracted some parameters from the linear model and analyzed the changes of the nucleotides' distributions. In order to facilitate the comparison of DNA sequences, we proposed two ways to measure their similarities. Finally, we compared the six models by analyzing the similarities of the DNA primary sequences presented in Table 1 and selected the optimal one. Β© 2007 Wiley Periodicals, Inc. J Comput Chem, 2007

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