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Lincomycin. XI. Synthesis and structure of clindamycin, a potent antibacterial agent

✍ Scribed by Birkenmeyer, Robert D.; Kagan, Fred.


Book ID
115458858
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
454 KB
Volume
13
Category
Article
ISSN
0022-2623

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Highly Diastereoselective Synthesis of 4
✍ Stefano Biondi; Angelo Pecunioso; Filippo Busi; Stefania A Contini; Daniele Dona πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 127 KB

AbstractÐIn this paper a highly diastereoselective synthesis of 4-N-methylformamidino trinem 3 is reported. The route offers advantages compared to that previously used, i.e. the higher overall yield, the robustness, the avoidance of toxic reagents. Most of the compounds were isolated by precipitati