The blood kinetics and tumour localization of a conjugate of methotrexate (MTX) and MAb 791T136 were examined i n nude mice with human tumour xenografts. The antibod moiety of the conjugate was detected by labelling with l2J and the drug moiety was assayed using a radioimmunoassay for methotrexate.
Limiting factors in the localization of tumours with radiolabelled antibodies
β Scribed by A.R. Bradwell; D.S. Fairweather; P.W. Dykes; A. Keeling; A. Vaughan; J. Taylor
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 941 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0167-5699
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