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Limited genetic evidence for MDR1 as a candiate gene for inflammatory bowel disease

✍ Scribed by Brant, Steven R.; Ramos, Richard; Bonen, Denise K.; Lubinski, Stuart M.; Ravenhill, Geoffrey; Rohal, Patrick M.; Lee, Sinda; Cho, Judy H.


Book ID
122605053
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
185 KB
Volume
118
Category
Article
ISSN
0016-5085

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Genetic analysis of MDR1 and inflammator
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Background: Single nucleotide polymorphisms (SNPs) in the multidrug transporter MDR1 have been associated with inflammatory bowel disease (IBD) in different studies. However, the data are highly controversial. Recently, 6 haplotype tagging SNPs (tSNPs), representing the haplotype variations of the M