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Evidence for a genetic defect in oral tolerance induction in inflammatory bowel disease

โœ Scribed by Thomas A Kraus; Adam Cheifetz; Dr. Lisa Toy; Jonathan B Meddings; Lloyd Mayer


Book ID
110087362
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
188 KB
Volume
12
Category
Article
ISSN
1078-0998

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It has become increasingly clear that inflammatory bowel disease (IBD) develops on the background of genetic defects in the host, conveying an increased susceptibility to an environmental antigen or antigens. The environmental factor implicated in the pathophysiology of gut inflammation, which is un