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Limited Cooperation between Peroxisome Proliferator-Activated Receptors and Retinoid X Receptor Agonists in Sebocyte Growth and Development

✍ Scribed by Mi-Jung Kim; Dianne Deplewski; Nancy Ciletti; Serge Michel; Uwe Reichert; Robert L. Rosenfield


Book ID
115639915
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
906 KB
Volume
74
Category
Article
ISSN
1096-7192

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## Abstract The peroxisome proliferator‐activated receptor‐α (PPAR‐α) plays a key role in lipid metabolism and inflammation. Recently, we demonstrated that administration of the PPAR‐α agonists gemfibrozil and fenofibrate, inhibit the clinical signs of experimental autoimmune encephalomyelitis (EAE