Structural Alterations in the 5โฒ Region
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Vasiliki Mikraki; Marc Ladanyi; Dr. R. S. K. Chaganti
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Article
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1991
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John Wiley and Sons
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English
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We report a new class of molecular lesions in the 5' region of the BCL2 protooncogene when it undergoes a t( 14; 18) translocation-associated rearrangement in the major break cluster (MBR) or minor break cluster (MCR) regions. Among 52 tumors assayed for BCL2 rearrangements using the MBR, MCR, and 5