Different fluorescence spectra are observed on preferential excitation of monomer and aggregate species of hematoporphyrin and hematoporphyrindiacetate, respectively. From these measurements we obtain the fluorescence spectrum of aggregate species in buffer solution, which shows two maxima, at 628 n
Light-induced transformations of hematoporphyrin diacetate and hematoporphyrin
✍ Scribed by Jurgita Rotomskien≐; Rūta Kapočiūt≐; Ričardas Rotomskis; Gediminas Jonušauskas; Tatiana Szitó; Alexandr Nizhnik
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 315 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1011-1344
No coin nor oath required. For personal study only.
✦ Synopsis
Illumination of hematoporphyrin diacetate (HP-Diac) and hematoporphyrin (HP) in phosphate-buffered solutions causes the formation of a stable photoproduct absorbing at 636 nm. Simultaneously the photo-oxidation of HP-Diac and HP takes place. These phototransformations depend on the illumination dose and the concentration of the HP-Diac or HP solution, and cause qualitatively the same spectral changes independently of the light source used.
📜 SIMILAR VOLUMES
Tbc blue-sbilicd emission from aged ~~IICOUS SO~II~~OIIS of hcmatoporphyrin and its derivatives. reporred by others to origimtc from special~ggrcg.!tcs, isshown to originate from the zinc chelates of the porphyrins. Sagestions arc made regxding the role of such zmc porphyrins in the localization of
The excited singlet and triplet absorption spectra of hematoporphyrin diacetate are presented. Extinction coefficients in the spectral range 420-700 nm are estimated. Two possible mechanisms of step excitation are proposed. The maximal stepexcitation efficiency is achieved at 450 nm.
A linear relationship was demonstrated between the reciprocals of the concentration of free hematoporphyrin and the moles of hematoporphyrin taken up by the platelet in the dark. Radiated platelets took up more hematoporphyrin than did controls; this increase in uptake was accounted for by the movem
The laser Raman spectra of the solid hematoporphyrin free-base HzHem, the diacid, [H4HemI2+ and the platinum complexes, [H4HemI2+ [PtCl4l2-, the Sitting-Atop complex (SAT), cis-Pt(H2Hem) Clz and the platino-hematoporphyrin PtHem have been studied in the range 500 to 1800 cm-l. The spectra of the pla