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Light-activated gene transduction of recombinant adeno-associated virus in human mesenchymal stem cells

✍ Scribed by Ito, H; Goater, J J; Tiyapatanaputi, P; Rubery, P T; O'Keefe, R J; Schwarz, E M


Book ID
110039398
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
228 KB
Volume
11
Category
Article
ISSN
0969-7128

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Recombinant adeno-associated virus 2 (AAV) vectors have proven to be a potentially useful alternative to the more commonly used retroviral and adenoviral vectors for gene therapy in humans. Their safety and efficacy in Phase I clinical trials for gene therapy of cystic fibrosis and hemophilia B have